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phosphorylation of Thr806 in SPT5 and also in the CTD of RNAPII were decreased after CDK9 inhibition 80,87,88 , and modest changes in phosphorylation of Ser2 and Ser7 were detected upon longer ( 1 h) CDK12/13 inhibition 78,81,89,90,91,92,93,94,95 (Fig
Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome
When MetS patients moved from atorvastatin to bezafibrate, endothelial function decreased (99)
Mathur, S., Agrawal, D
Disulfide-linked polymerdrug conjugates and nanocarriers engineered for GSH-triggered drug release have shown favorable safety and preliminary efficacy profiles, highlighting the feasibility of translating redox-responsive strategies into clinical practice [120]
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