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A licensed prescriber sends a prescription to Hallandale, the pharmacy compounds it, and ships the finished product

GLP-1 helps regulate blood sugar by stimulating insulin release, suppressing glucagon (which raises blood sugar), and slowing gastric emptying

In anticipation of this publication, a mathematical model was developed, and the results of the SOUL trial are predicted by this study

doi: 10.1038/nature11053 15 RampelliSSchnorrSLConsolandiCTurroniSSevergniniMPeanoCet al

But the reviewers graded the evidence as very low quality, with high risk of bias, and the trials were concentrated in a handful of countries: three in China, one in Russia, one in Romania, one unclear