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Administration of anthracyclines results in acute, early-onset, and delayed-onset cardiotoxicity, and the risk of developing heart failure increases as the cumulative doses increase, but in some cases, it can occur more than two decades after medication therapy has been completed

At 32 weeks, 48.0% of participants on mazdutide 6 mg achieved both HbA1c below 7% and at least 10% body weight reduction, compared to just 21.0% on semaglutide 1 mg