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Effect of peripheral neuropathy on bone mineral density in adults with diabetes: a systematic review of the literature and meta-analysis

The SURMOUNT trials demonstrated that participants on tirzepatide maintained significant weight loss over 68 weeks, with many physicians prescribing it as ongoing maintenance therapy rather than short-term intervention

ABSTRACT KEY FIGURE Highlights INTRODUCTION DISCOVERY OF GLP-1 AND DEVELOPMENT OF INCRETIN-BASED DRUGS GLP-1 AND IMPLICATIONS IN COGNITIVE SATIATION: HUMAN STUDIES HYPOTHALAMIC FUNCTIONS IN COGNITIVE FEED-FORWARD REGULATION HYPOTHALAMIC CONTROL OF GLP-1 ACTIONS ON SATIATION AND SATIETY: ANIMAL STUDIES ONGOING FUTURE STUDIES OF GLP-1R AGONISTS NOTES REFERENCES About this article ABSTRACT Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have emerged as blockbuster drugs for treating metabolic diseases

The association remains largely observational and patient-reported rather than formally quantified in controlled studies

Spacing doses, taking metformin with food, and starting at low GLP-1 doses help minimize symptoms