( C ) Mouse caSMCs were pretreated with 100 nM GLP-1(2836) or scrambled control for 20 minutes followed by incubation with H 2 O 2 (100 M) for 48 hours to induce oxidative stress ( n = 3/each, in triplicate)
Coles BF, Morel F, Rauch C, Huber WW, Yang M, Teitel CH et al
2a, b) highlights the importance of the bioavailability of cysteine to enable cells to adapt to metabolically challenging conditions, as well as mediating cancer cell survival, tumour growth, metastases formation, resistance to therapy and disease recurrence
This is the first study of its kind for fibromyalgia, there was no comparison to existing approved fibromyalgia treatments, and the dose to effect relationship in rats doesnt translate directly to humans
Patients with pre-existing mental health conditions should be monitored closely when starting Ozempic, and any new or worsening mood symptoms should be reported to a healthcare professional promptly