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Glutathione protective mechanisms Recently, studies have further demonstrated the negative effects of oxidative stress and impaired redox signaling in the onset of OA, aggravating significant oxidative damage of cellular structures and vital molecules in cartilage as well as other tissues

S3, Table S5), with the majority of studies focusing on a specific GLP-1RA drug, including 12 on exenatide, 2 on lixisenatide, 3 on dulaglutide, 1 on albiglutide, and 1 on semaglutide

Still, several indirect factors may require attention when both treatments are used

Prolonged disequilibrium of NAD + metabolism disturbs the physiological functions, resulting in diseases including metabolic diseases, cancer, aging and neurodegeneration disorder

Pervasive Players 45 11.4.4