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Practice Pearl For the management of hyperkalemia, use all possible interventions to lower potassium level before discontinuing or dose reducing RAAS inhibitors

JAMA 2014;312:380-389

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We show that [human TAAR5] responds to the tertiary amine N,N-dimethylethylamine and to a lesser extent to trimethylamine, a structurally related agonist for mouse and rat TAAR5 (Liberles and Buck, 2006