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Recent insights into GLP-1R signaling in beta cells is summarized in (115)

Like other weight-loss drugs, it's to be used along with exercise, a healthy diet and other steps like keeping a food diary

In addition to detoxification, GSH plays a role in other cellular reactions, including, the glyoxalase system, reduction of ribonucleotides to deoxyribonucleotides, regulation of protein and gene expression via thiol:disulfide exchange reactions [2]

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The major obstacles to developing probes that can monitor GSH dynamics include the reaction reversibility and kinetics of the sensing reaction, as well as the high abundance of GSH (110 mM) inside cells