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The higher dietary fat intake (9weeks duration) of HFD-fed recipients did not result in differences in percent body weight gain, endocrine parameters (insulin, estradiol, and progesterone), and estrous cyclicity, relative to CD-fed recipients, indicating the preferential contribution of the local peritoneal environment rather than the systemic milieu to underlie the differences in lesion parameters

Muscle Tissue and Hypertrophy Research Muscle tissue research on IGF-1 LR3 focuses on two distinct mechanisms: hypertrophy of existing muscle fibers and satellite cell activation, which can contribute new fibers rather than simply enlarging existing ones