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Because nerves heal slowly, researchers often look at timelines of 4 to 12 weeks to see significant changes in nerve density

Glutathione efflux from perfused rat liver after phenobarbital treatment, during drug oxidations, and in selenium deficiency

Regarding polymeric nanoparticles, chitosan is an FDA-recognized biopolymer cleared for use in wound-healing devices and with limited Generally Recognized As Safe (GRAS) status in specific food applications, also widely investigated for drug delivery systems (Shah et al., 2025