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The primary outcome measure was the change in melasma severity as assessed by a mexameter, which measures melanin content in the skin, and the Melasma Area and Severity Index (MASI), which is a score based on the area, darkness, and homogeneity of pigmentation

Given Semaglutides proven efficacy in treating conditions associated with metabolic dysfunction and its impact on gastrointestinal physiology, its potential utility in IBS presents a novel area of clinical research