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DMI is widely recognized for its ability to stimulate the activation of Nrf2 and enhance the production of Nrf2 protein [7]

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Glutathione is a tripeptide, consisting of the three amino acids, cysteine, glutamic acid, and glycine

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In the aforementioned study from our group, adult mice with partial IGF-1 also displayed decreased expression of genes involved in lipid metabolism (ATP-citrate lyase, acetyl-CoA acyltransferase 1B, acetyl-CoA acetyltransferase 1) and cholesterol synthesis and transport (Both HMG-CoA reductase and synthase, LDL-related protein 1, proprotein convertase subtilisin/Kesin type 9), resulting in dyslipidaemia