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The approval was based on positive Phase 3 clinical trials, which evaluated the safety and efficacy of SUTAB compared to FDA-approved preparations in 941 patients, including a traditional polyethylene glycol and ascorbate preparation (PEG-EA) for bowel cleansing prior to a colonoscopy

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[DOI] [PMC free article] [PubMed] [Google Scholar] 28.Freitas H.R., Ferraz G., Ferreira G.C., Ribeiro-Resende V.T., Chiarini L.B., do Nascimento J.L., Matos Oliveira K.R., Pereira Tde L., Ferreira L.G., Kubrusly R.C., et al

[12] Adverse effects [edit] Preclinical, phase I, and phase II clinical trials indicated that tirzepatide exhibits adverse effects similar to those of other established GLP-1 receptor agonists, such as dulaglutide (sold as Trulicity) and semaglutide (sold as Wegovy, Ozempic, and Rybelsus)