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Moreover, compared with animal studies, the pharmacological data and rigorous clinical trial evidence of Th17/Treg regulation in human AR patients are significantly insufficient

They are thus controlled in a different manner as compared to pharmaceutical drugs

3-A pesar de supuesta bondad de la mesoterapia en el tratamiento de la celulitis y de la existencia de estudios experimentales que sugieren la plausibilidad biolgica de la misma en aquella condicin, en virtud de su capacidad para aumentar la liplisis, remodelar el tejido conectivo y aumentar la ciculacin, no existen ensayos clnicos rigurosos que hayan demostrado dichos efectos (1,2)