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Reduced appetite suppression, unexpected side effects, or injection site reactions that differ from your normal experience could indicate that the medication has degraded

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Patients should seek medical attention if they experience severe or persistent gastrointestinal symptoms, signs of pancreatitis (severe abdominal pain radiating to the back), symptoms of thyroid tumors (neck mass, difficulty swallowing, persistent hoarseness), right upper quadrant pain, jaundice, reduced urine output, or unexplained hypoglycemia

Clinical remission was defined as a Crohn's Disease Activity Index (CDAI) score below 150, indicating low disease activity

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