There is increasing evidence that the gastrointestinal microbiota is influenced by GLP-1 signaling in a bidirectional manner
A systematic review demonstrates that participants using retatrutide reported a higher incidence of nausea, decreased appetite, constipation, diarrhea, and vomiting
We first confirmed that the HaCaT-GFP-BAP cells were efficiently depleted for GSH upon treatment with BSO (Table 1) and that this led to inhibition of HPV16 infection as observed with parental HaCaT cells (Fig 5A)
For topical use, transient local reactions redness, stinging, burning, or itch are the expected category and are exactly what the ongoing Phase 2 trial is set up to measure (NCT07437586)
however, claims that a specific ingredient helps people taking GLP-1 medications maintain muscle should be made only if supported by evidence for that population and use context