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We hypothesize that SAC inhibits the E3 ubiquitin ligase activity of KEAP1 through interaction, thereby blocking the ubiquitination-mediated degradation of NRF2, stabilizing the NRF2 protein, and activating the transcription of various protective genes, including antioxidant enzymes

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A number of companies are already active in this space in China where the patent for liraglutide has already expired

Administration method depends on experimental design

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