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Upregulated Wnt/-catenin signaling expression by morroniside in HFs in the telogen-to-anagen and anagen-to-catagen transition stages To further evaluate whether the expression of Wnt/-catenin signaling was also influenced by morroniside (100 M) in HF cycling transition, we performed IHC analysis of murine HFs, and the results revealed that -catenin staining in the morroniside-treated group was more intense than that in the control group throughout the epidermis, ORS and hair matrix (Fig

Vitamin Treatment of Hyperhomocysteinemia Hyperhomocysteinemia can be reduced significantly or reversed by vitamin treatment of affected patients, except those bearing severe functional defects of methionine synthase or a thermostable mutation of MTHFR