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Zhao HM, Hu RW, Du H, Xin XP, Li YW, Li H, Cai QY, Mo CH, Liu JS, Zhou DM, Wong MH, He ZL (2018a) Functional genomic analysis of phthalate acid ester (PAE) catabolism genes in the versatile PAE-mineralising bacterium Rhodococcus sp

This leads to peripheral and hepatic insulin resistance and compensatory intra-portal hyperinsulinemia, which results in increased hepatic GH sensitivity that aggravates the condition further ( Table 1

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These findings underline the causative role of the microbiome in weight and metabolic changes