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In animals studies, BPC-157 has been administered in the following ways: To rats at a dose of 10 mcg/kg via injection [12] To mice at a dose of 10 g or 10 ng/kg body weight intraperitoneally (i.p.) via injection [14] To mice as a thin layer of cream topically (50 g of BPC 157 dissolved in 2 ml of distilled water with 50 g of commercial neutral cream and 1% white silver sulfadiazine)

The gut-brain axis research suggests BPC-157 interacts with broader systemic regulation beyond local tissue effects

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