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Causality is not proven, but chronic daily use should be minimized

Creatinine levels typically rise when: the kidneys cannot filter it efficiently due to reduced glomerular filtration rate (GFR), dehydration temporarily reduces renal blood flow, creatine supplements increase creatine turnover, intense exercise or large muscle mass increases baseline production, or certain medications (like NSAIDs or contrast dye) reduce kidney blood flow

Neuropsychiatric consequences of cardiovascular medications

230 In high-fat diet-induced MASLD models, naringin improves liver function, reflected by decreased serum ALT and AST levels

They are not intended to diagnose, treat, cure or prevent any disease