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In mice, SFB can protect the host by promoting colonization resistance against a wide array of pathogens in the gut 3,97 and more recently also in the lung 12,13,98 while also exacerbating disease severity in models including autoimmune encephalitis 18 , obesity-induced liver damage 19 , autoimmune arthritis 17,20 , depression 42 , Crohns disease 15 , and autism 16

& Kearney, J

10), these results collectively suggest that GSH and Glu may bind to different domains of GLR3.3 for activating ion channel activity and triggering leaf-to-leaf, calcium-based plant defense signaling

The long non-coding RNA MALAT1 suppresses NRF2 expression through epigenetic mechanisms, promoting inflammasome activation and ROS production in Parkinsons disease (PD) mouse and microglial cell models, thereby exacerbating neuroinflammation [168]

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