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The sublingual delivery route administers MT-II to the mucosa beneath the tongue, where the dense sublingual vasculature allows for systemic peptide absorption without the hepatic first-pass metabolism that limits oral bioavailability in most peptide formulations

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Study 4: Cone 2006, receptor biology Citation: Cone R.D

Journal of pharmaceutical and biomedical analysis, 2008, 47(3): 596- 602

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