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Diabetologia (2001) 44:32532

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Staying on the same dose for longer, delaying a dose increase, or reducing the dose may be considered if side effects are difficult to manage, but it should always be discussed with your doctor

ROS from leukocytes can induce lipid peroxidation in sperm membranes, leading to decreased membrane fluidity, impaired motility, and compromised sperm-oocyte fusion