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A study in 49 people with knee osteoarthritis found that taking 3.4 grams of MSM per day for 12 weeks reduced pain and stiffness and improved physical function, compared to a placebo ( Additionally, it can enhance the effectiveness of other common supplements used to treat arthritis such as glucosamine sulfate, chondroitin sulfate and boswellic acid

Popular options include Coenzyme Q10 (CoQ10) for mitochondrial energy production, magnesium for muscle function and relaxation, and adaptogenic herbs like ashwagandha and Rhodiola Rosea for stress adaptation