Individual safety findings for one molecule dont necessarily predict class-wide effects, says Finer, safety signals often relate to specific structural features or off-target activities rather than the primary mechanism of action. He thinks oral GLP-1 drugs have the potential for better dose titration, which might help control the current, mainly gastrointestinal, side-effects of the injectable peptides
Those taking oral semaglutide (Rybelsus) should discuss the 30-minute pre-food, pre-medication timing requirement with their healthcare provider
pcdeurope.org), Diabetes and Cardiovascular Disease Study Group (DCVD, www.dcvd.org), Forschergruppe Diabetes e
doi:10.1177/23247096211051919 Kommu S, Whitfield P
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