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Hepatocyte growth factor (HGF) attenuates gliosis and motoneuronal degeneration in the brainstem motor nuclei of a transgenic mouse model of ALS
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In animal models, preclinical work has also documented antinociceptive effects (attributed to indirect Met-enkephalin release [7]), antioxidant enzyme stimulation [11], and inhibition of hypothalamic somatostatin secretion [8]
Diet plays a multifaceted role in the connection between the epigenome, thyroid function, and gut microbiota, exerting both direct and indirect effects on each of these systems [148,149]
Response: While these comments are out of scope for this final rule, we acknowledge commenters' concerns with identifying patients, operationalizing Medicare CQMs, and with having vendor issues
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