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Prices for semaglutide the brand name for buzzy prescription injections such as Ozempic and Wegovy are far higher in the US than they are in the UK and more than a dozen countries across the globe, according to a recent study published in the journal Obesity
Women of reproductive age Semaglutide is contraindicated during pregnancy and should be discontinued at least two months before a planned pregnancy
Reference: Weight regain after cessation of medication for weight management: systematic review and meta-analysis by Sam West, Jadine Scragg, Paul Aveyard, Jason L Oke, Lia Willis, Stella J P Haffner, Heather Knight, Danni Wang, Sarah Morrow, Laura Heath, Susan A Jebb and Dimitrios A Koutoukidis, 7 January 2026, BMJ
Studies examining the efficacy of GLP-1 drugs used for weight loss have generally quantified changes in fat and lean mass, with changes in lean mass serving as a surrogate for muscle mass