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There are 4 major endogenous estrogens in humans: estrone (E1), 17-estradiol (E2), estriol (E3), and estetrol (E4)

Blue light, the high-energy short-wave light, can penetrate the cornea and lens, reaching the retina and ultimately inducing photochemical damage 16,20

In a diabetic mouse model, it reduced oxidative stress-induced neuropathy by triggering antioxidative defense signals (Agca et al

Wickham S, West MB, Cook PF, Hanigan MH

Topiramate attenuates dural vasodilation primarily by inhibiting nitric oxide-mediated release of CGRP from preganglionic fibers of the trigeminal nerve ( 5 The relationship between migraine, oxidative stress, and neurogenic inflammation According to the theory of migraine genesis, the majority of migraine triggers have the ability to cause oxidative stress in the body