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Selectively reducing Gsto2 in iSPNs in vivo effectively prevented dopaminergic dysfunction and halted the onset and progression of hyperkinetic symptoms

Citronellol, Hydroxycitronellal, Limonene, Linalool: These are fragrance components that can also occur naturally in essential oils

The single most common source of disappointment with a compound like KLOW is expecting a fast, dramatic, visible change

In addition, animals in different groups showed a similar weight gain during the course of the experiment (Table S2)

Furthermore, C1-27 bound GSTO1 more potently than PDI and showed a 100-fold more potent inhibition of its enzyme activity (Fig