NRF2 orchestrates the upregulation of several antioxidant genes reliant on GSH, including GSR, solute carrier family 7 member 11 (SLC7A11), glutamatecysteine ligase catalytic subunit (GCLC), and glutamatecysteine ligase modifier subunit, as well as metabolic detoxification genes such as aldehyde dehydrogenase 1 family member A1 and aldoketo reductase family 1 member C1 in cancer cells [66]
Takeaway: If peptides were tools, GHK-Cu would be the precision paintbrush that perfects the finish after the heavy lifting is done
For a more comprehensive breakdown, our guide on supplementation during GLP-1 agonist use covers additional considerations including B-vitamins, probiotics, and digestive support
Estrogen is a primary stimulator of fibroblast collagen synthesis, which is part of why post-menopausal women experience accelerated skin collagen loss
Researchers classify it as a "stable gastric pentadecapeptide" because of its unusual stability in the harsh acidic environment of the stomach
