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A 15-year follow-up study published in the Bulletin of Experimental Biology and Medicine (Khavinson et al., 2011) examined the geroprotective properties of pineal-derived peptides, with findings supporting long-term benefits on aging trajectory

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This work represents one of the first demonstrations of FOXO4-DRI activity in primary human cells, supporting translational relevance beyond the initial mouse model findings

Peptides for Targeting Chondrogenic Induction and Cartilage Regeneration in Osteoarthritis, Liao H.J., Chen H.T., Chang C.H., Journal (Cartilage, September 2024, Epub ahead of print)

Freeman, PhD, explains that your mental health history factors into your risk: Women with a history of depression are nearly five times more likely to have a diagnosis of major depression in the menopausal transition, whereas women with no history of depression are two to four times more likely to report depressed mood compared with premenopausal women. Estrogen helps to support feel good brain chemicals, such as serotonin and norepinephrine, responsible for mood stabilization, alertness and energy