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Adipose tissue, particularly visceral fat surrounding internal organs, actively produces inflammatory molecules called cytokines

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Investigation of potential mechanisms regulating protein expression of hepatic pyruvate dehydrogenase kinase isoforms 2 and 4 by fatty acids and thyroid hormone

Metformin reduces hepatic glucose production, decreases intestinal glucose absorption, and increases peripheral insulin sensitivity, and may reduce appetite by raising glucagon like peptide-1 levels