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Indeed, Yun and co-workers found that the intracellular reduction of DHA back to vitamin C depleted the cellular stores of reduced glutathione (GSH, the major antioxidant in cells), leading to an increase in reactive oxygen species (ROS)

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It is still unclear how, where, and when these culminate in cell death

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The depth and visibility of the Cupids bow depend on factors such as upper-lip fullness, skin and tissue thickness, philtral column definition, and how the lip muscles support the upper lip