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Liver fat, visceral fat, lipids, ketones, and insulin are real and measured, but no retatrutide trial has tested insulin sensitivity or longevity as an endpoint

"We really don't know those answers." But Reichert said she's excited about where the field seems headed: the possibility of better access to medications , such as a pill, lower prices as well as behavioural programs from insurance companies coupled with efforts to reduce the shame and bias people with bigger bodies face to support healthy lifestyle changes

Additionally, SubQ injections are generally less painful

average body weight lost over 74 weeks In a study of 3,127 adults over half lost at least 10% of their body weight