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Further, a pre-clinical study of metastatic lung cancer reported that TDLNs help control metastases after the primary tumor is removed but are not required for adjuvant immunotherapy efficacy (235)

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Potential Research Applications: Growth hormone secretion and lipolysis studies Visceral adipose tissue and metabolic research models Body composition and anti-aging investigations Cardiovascular risk factor and insulin sensitivity studies For laboratory research only

During systemic infection in mice, mutants with limited glycolytic flux are not toxic