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Rotating injection sites, allowing alcohol to dry before injection, and using appropriate needle gauge minimizes local reactions

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Wegovy, made by the same manufacturer, is the only semaglutide approved for weight management in young people aged 12-18, and only in addition to a reduced-calorie diet and increased physical activity

Most GLP-1 receptor agonists, including semaglutide and tirzepatide, are administered once weekly as injections, though oral formulations taken daily have also become available

GLP-1 receptor agonists are a novel class of pharmacological agents for obesity and T2D