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7.3 Azelaic acid, 4-n- butyl resorcinol, and retinol The clinical effectiveness of a liposomal serum containing azelaic acid, 4-n-butylresorcinol, and retinol was assessed in patients with malar pattern melasma

They are not inevitable or irreversible, but they do warrant attention rather than being treated as an acceptable side effect to push through

This is how entire studies get derailed