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As noted by Hausners team: "No clinically significant pharmacokinetic or pharmacodynamic interactions were identified This suggests that no dose adjustments should be required when semaglutide is administered concomitantly with these medications." Other findings support this consistency

We did not select either males or females in our studies because the murine models here used have not been reported to show differences in the progression of the disease between sexes, as also reported in patients with mutations in the PDE6 enzyme or P23H mutation in rhodopsin

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