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full activity consideration with clearance Physical therapy is essential and dramatically improves outcomes Avoid NSAIDs for 2-6 weeks minimum Follow structured progression rather than subjective feelings How Should You Use This Timeline With Your Doctors Instructions

Three times daily systemic (SC) treatment of DIO mice with 20 mg/kg of 5-amino-1MQ produced a progressive loss of body weight over the treatment period compared to controls (Figure 5A)

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