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[4] Cold is most effective at relieving pain and swelling during the first 3 days after the injury, but after that, using heat can help relax the area and may increase circulation, which can promote healing

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TABLE 10 Structures of six metabolites identified by high-performance liquid chromatography-tandem mass spectrometry in rat plasma, bile, urine, and feces following a single intramuscular administration of 100 g/300 Ci/kg of [3H]BPC157