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Pharmaceutical GLP-1 agonistssuch as semaglutidehave become popular, but they are synthetic, require prescriptions, and may carry side effects with long-term use

Similarly, finding from other studies demonstrated the ability of the autophagy activator, metformin to attenuate CP-induced ototoxicity, cardiotoxicity, and neurotoxicity primarily through AMPK activation (Liang et al., 2021

When medication is prescribed, fulfillment depends on clinical eligibility, legal availability, and pharmacy requirements

The JAK2/STAT3 and ERK pathways were involved in the possible molecular mechanism

As for the data it provides from clinical trials, these have been approved by regulatory agencies such as the all-powerful FDA, which is a sign of assurance in terms of their design