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Skin lightening creams and intravenous or oral glutathione do not offer reasonable clinical benefit over placebo effect, are not associated with long term improvements, harbor potential adverse events (heavy metal toxicity and renal injury) or lack safety data (intravenous glutathione) and hence, not recommended (98100)

By implementing effective moisture control measures, the risk of hydrolysis and other moisture-induced degradation processes can be minimized

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Also a separate standard plot was prepared in water for same concentration of 20ppm, 40ppm, 60ppm, 80ppm, lOOppm