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2324 Product of Malaysia PRINCIPAL DISPLAY PANEL 100 units/mL Pen NDC 83257-012-33 Rx only Semglee (insulin glargine-yfgn) injection For Single Patient Use Only 100 units/mL (U-100) For subcutaneous use only Dispense in this sealed carton Do not mix with other insulins Use only if solution is clear and colorless with no particles visible *Needles not included (see top panel) Five 3 mL Prefilled Pens Each mL contains 100 units of insulin glargine-yfgn, and inactive ingredients: glycerol (20 mg), metacresol (2.7 mg), zinc chloride (content adjusted to provide 30 mcg zinc ion), and Water for Injection, USP

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Peptides are typically supplied as lyophilized (freeze-dried) powders and require reconstitution with a sterile solvent, such as bacteriostatic water

Lumps or hard spots under the skin Firm lumps, nodules, or hardened areas near injection sites can develop for several reasons