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In addition to promoting matrix synthesis, IGF-1 inhibits the activity of enzymes that break down cartilage, such as matrix metalloproteinases (MMPs)

38-40 A multicenter study of 709 patients with COPD in China (PEACE study) treated with placebo or 1500 mg carbocisteine per day for 1 year demonstrated a reduction in the number of acute respiratory exacerbations in the active drug group

Loss of integrity in the fornix in schizophrenia is a robust finding, 4, 18, 19, 20, 21, 22, 64 although with mixed results in childhood and adolescent schizophrenia

Role of cystoscopy and hydrodistention in the diagnosis of interstitial cystitis/bladder pain syndrome

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