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We have previously discovered that combinations of BBB nutrient transporter ligands alanine and glutathione (A-GSH), increase the permeability of vesicular and polypeptide nanocarriers containing model cargo across the BBB

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Tlholoe MM, Khammissa RA, Bouckaert M, Altini M, Lemmer J, Feller L

Hold the vial or pen up to a light source and examine the solution carefully