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As binding proteins, IGF-1 and IGF-2 both bind to and activate different receptors, causing the growth of different cells and tissues

24 In neurodegeneration, where proteostasis collapse is strongly associated with disease progression, enhancing resilience through multi-pathway modulation may slow pathological decline

Med 21 , 590 (2023)

Medical weight loss with FDA-approved GLP-1 medications works differently because it addresses the hormonal drivers of appetite, not just willpower