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Medical and regulatory references: FDA announcement on Foundayo/orforglipron approval JAMA report on FDA approval of oral orforglipron Novo Nordisk announcement on Wegovy pill approval and OASIS 4 results New England Journal of Medicine: Oral semaglutide 25 mg in adults with overweight or obesity JAMA Surgery: Obesity treatment with bariatric surgery vs GLP-1 receptor agonists NIDDK: Prescription medications to treat overweight and obesity ASMBS patient resources on metabolic and bariatric surgery

Not necessarily all of it, but most patients regain a significant portion without lifestyle changes and ongoing monitoring

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Statements Data availability statement The original contributions presented in the study are included in the article, further inquiries can be directed to the corresponding author