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In DFU, notch pathway dysfunction can lead to inhibition of cell differentiation, proliferation disorders, and reduced angiogenesis, all of which interfere with diabetic wound healing

However, the pro-regenerative role of the mTORC1/S6K signaling pathway overwhelms the antiproliferative role of the p53/p21 signaling pathway in Wip1 deficient mice

10.1002/clc.2326631571239 131 Li L, Tian X, Gao Y, et al

coli using a number of expression vectors specifically designed for E

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