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Early identification and treatment can help to avoid problems 1,2,3

Nat Commun 2016;7:11457

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use with caution in mixed drug overdoses.8 hours: 6 mg or 6 x 1 mg/10 mL vials24 hours: 12 mg or 12 x 1 mg/10 mL vialsImmediate emergency departmentFomepizole (4-MP)/ AntizolPreferred antidote for ethylene glycol or methanol poisoningManufacturer of Antizol will replace expired stocks8 hours: 1.5 g or 1 x 1.5 mL (1 g/mL) vials24 hours: 4.5 g or 3 x 1.5 mL (1 g/mL) vialsWithin 1 hourGlucagonBeta blocker/calcium channel blocker poisoningAnticipate nausea and vomiting8 hours: 90 mg or 90 x 1 mg vials24 hours: 250 mg or 250 x 1 mg vialsImmediate emergency departmentGlucarpidase/ VoraxazeMethotrexate toxic levelsUse in patient with toxic levels and impaired renal function